Urinary hydroxyproline excretion in myelofibrosis
نویسندگان
چکیده
منابع مشابه
Urinary hydroxyproline excretion in myelofibrosis.
Urinary hydroxyproline measurements were performed in a group of health volunteers as well as patients with cancer and myelofibrosis. Patients in whom there was no metastatic involvement of bone marrow excreted an amount of hydroxyproline not different from that of the control group. Those who had marrow metastasis produced elevated levels of hydroxyproline; the highest excretions were observed...
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Urinary excretion of hydroxyproline has been studied in patients with different types of leprosy. The mean average daily excretion is highest in lepromatous leprosy as compared with other forms of leprosy or normal controls. The most striking feature is the “spiky” pattern of the excretion with very wide fluctuations in the daily output observed in lepromatous leprosy patients in reaction. This...
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H. RESNICK, N. L. LAPP, AND W. K. C. MORGAN Cardiopulmonary and Biochemistry Units of the Medical Research Section, Appalachian Laboratory for Occupational Respiratory Diseases, Morgantown, West Virginia, Bureau of Disease Prevention and Environmental Control, National Center for Urban and Industrial Health, Public Health Service, U.S. Department of Health, Education and Welfare, and the Depart...
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Both amniotic fluid and urine of newborns contain .hydroxyproline, an amino-acid related to the collagen metabolism and particularly the collagen matrix. Phases of rapid growth of the human body are accompanied by a high collagen turnover resulting in an increased excretion of hydroxyproline in the urine, whereas malnourishment and retarded growth lead to a diminished output [11,15]. In normal ...
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The significance of urinary hydroxyproline has not been completely clarified. It appears, however, that this amino acid excretion is correlated with either synthesis or destruction of collagen. Collagen hydroxyproline is reported to be formed by the irreversible hydroxylation of peptid-linked proline and no free hydroxyproline is incorporated directly into this protein. Therefore, the changes o...
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ژورنال
عنوان ژورنال: Blood
سال: 1980
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v55.3.383.bloodjournal553383